Professor Henry Mak joined The University of Hong Kong in 2007 and is currently Clinical Associate Professor of Practice in the Department of Diagnostic Radiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU).

He obtained his MBChB (1989) from the Chinese University of Hong Kong and MD (2015) from HKU. His MD thesis was on ‘Advanced Magnetic Resonance Imaging techniques in the diagnosis of Alzheimer’s Disease (AD), and evaluation of AD pathogenesis in an aging brain’.

He is a diagnostic neuroradiologist and was Clinical Instructor in the Division of Neuroradiology of Department of Radiology, University of Virginia Medical Center (USA) from March 2011 to February 2012. He was the Chief of Service of the Medical Imaging Department of the HKU-Shenzhen Hospital (2017-2022).

His interests are in functional neuroimaging; especially advanced magnetic resonance techniques such as Volumetric MRI, MR perfusion using Arterial Spin Labeling (ASL), Susceptibility-Weighted Imaging (SWI), brain connectivity (rs-FMRI), Chemical Exchange Saturation Transfer (CEST) and MR Spectroscopy (MRS), and their applications in Alzheimer's and other neurodegenerative diseases, stroke, Multiple Sclerosis/Neuromyelitis Optica and brain tumors.

He had around 245 peer-reviewed published works, including 1 book chapter, 122 peer-reviewed journal articles (such as Stroke, Radiology, Neurology, Journal of Alzheimer’s Disease, Schizophrenia Research, NeuroImage Clinical etc.) and 122 conference abstracts; and had given 28 invited talks overseas. He is Editor of the Hong Kong Medical Journal, & American Journal of Alzheimer’s Disease and Other dementias, Associate Editor of American Journal in Nuclear Medicine and Molecular Imaging, and Editorial Board member of Brain Sciences.

He had been Council Member of the Hong Kong Neuro-Oncology Society, Hong Kong Neuroimmunology Society, and Asian Society of Magnetic Resonance Imaging.

Prof K H Chan received his training in internal medicine and neurology in the University Department of Medicine, Queen Mary Hospital, Faculty of Medicine, the University of Hong Kong. He obtained his fellowship in neurology in 2001 and after staying one year of elective research on neuroimmunological disorders and related neuroimmunology focusing on neuronal and muscle autoantibodies in paraneoplastic neurological disorders and myasthenia gravis under the mentorship of Professor Vanda A Lennon in Mayo Clinic Rochester in 2000. He obtained his MD in 2007 and PhD in 2012 from HKU, and joined the University of Hong Kong as Clinical Assistant Professor in 2008, became Clinical Associate Professor in 2013 and was promoted to Clinical Professor in 2024.

His research interests include autoimmune neurological disorders and related neuroimmunology, and neuroinflammation of Alzheimer’s disease. Multiple sclerosis (MS) is an important inflammatory demyelinating disorder of the central nervous system (CNS) with uncertain pathogenesis. Neuromyelitis optica spectrum disorders (NMOSD) cause severe acute myelitis, optic neuritis and encephalitis especially brainstem encephalitis, and can be misdiagnosed as MS. Detection of aquaporin-4 autoantibodies (AQP4-IgG) in serum of NMOSD patients greatly facilitate the diagnosis of NMOSD and its differentiation from MS. APQ4 is the most abundant water channel protein in mammalian CNS, which is expressed abundantly in astrocytic endfeet processes. NMOSD are more common among Asians with long-term treatments different from that of MS. K H Chan’s current research focuses on 1) clinical and radiological features of local MS and NMOSD patients, 2) understanding immunopathogenesis of MS and NMOSD especially the pathogenic role of AQP4-IgG, 3) development of novel immunotherapies for MS and NMOSD, 4) understanding the pathogenetic mechanisms/pathophysiologies of Alzheimer’s disease (AD) and 5) development of novel personalized therapeutics for AD and other neurodegenerative diseases causing cognitive impairment and dementia. He is particularly interested in the role of B cells in MS and NMOSD. He participates in international multi-center trial on new disease modifying therapies for MS and NMOSD. His team first reported that brainstem encephalitis is common among Hong Kong Chinese NMOSD patients (Arch Neurol 2010). He is actively researching on the pathogenetic mechanisms/pathophysiologies of Alzheimer’s disease (AD) focusing on microglia-mediated neuroinflammation triggered by beta-amyloid (Aβ) and tau, and dysfunction of the glymphatic system. He is exploring the potential neuroprotective effects of adiponectin (an adipokine with anti-inflammatory and insulin-sensitizing properties) and measures to improve glymphatic functions as strategies to prevent and treat AD. Professor Chan’s laboratory discovered the role of adiponectin in cognition of the mammalian brain (Mol Neurodegener 2016) and that microglia express adiponectin receptors with adiponectin signaling activity leading to anti-inflammatory effects in microglia (J Neuroinflam 2019).

​​​Dr. Yat-fung Shea is the consultant geriatrician in Queen Mary Hospital since 2022. He is specialized in dementia care with a special interest in the application of biomarkers for Alzheimer’s disease, familial Alzheimer’s disease and the application of anti-amyloid therapies in Hong Kong.

Prof Eva Cheung currently serves as an Assistant Professor in the Department of Diagnostic Radiology at the LKS Faculty of Medicine, The University of Hong Kong. With a diverse academic background and extensive experience in medical imaging and radiotherapy, She has made significant contributions to both research and clinical practice.

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Her academic journey began iwhen she earned a Bachelor of Science in Radiography (Therapeutic) from Hong Kong Polytechnic University. Later, she expanded her expertise by completing a Master of Science in Business Information Technology at Middlesex University in the United Kingdom. Her passion for medical engineering led her to pursue further studies, obtaining a Master of Science in Biomedical Engineering from The Chinese University of Hong Kong and a Master of Science in Medical Engineering & Physics from King’s College London. She later completed her Doctor of Philosophy at The University of Hong Kong.

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Beyond academia, she has gained extensive professional experience in clinical settings, research, and leadership roles. She has served as a Senior Lecturer and Senior Clinical Associate at Tung Wah College. She has also held the role of Assistant Professor and Deputy Program Leader for the Radiation Therapy program. In 2023, she was a Visiting Scholar at Glasgow Caledonian University in Scotland. Her earlier career included positions such as Senior Dosimetrist in Oxford, Medical Physicist Trainee in Radiotherapy at Guy’s and St. Thomas’ NHS Foundation Trust in London, and Radiation Therapist at both HK Baptist Hospital and Gleneagles Hospital in Singapore. 

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Her research interests focus on the development of advanced imaging techniques for neurodegenerative diseases, including functional MRI and imaging biomarkers. She is particularly interested in artificial intelligence applications for dementia diagnosis and treatment optimization, as well as cancer imaging, radiotherapy treatment planning, and AI-driven cancer prognosis prediction.

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Over the years, she has secured multiple research grants, including funding from the Alzheimer’s Association and the Foundation of the American Society of Neuroradiology, as well as the Faculty Development Fund from the University Grants Committee in Hong Kong. Her work has led to numerous peer-reviewed publications in leading scientific journals, with significant contributions to neuroimaging and cancer research.

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With her deep expertise in radiotherapy, biomedical engineering, and artificial intelligence applications, [Name] continues to drive advancements in medical imaging and patient care.

Dr Jianpan Huang is an assistant professor in the Department of Diagnostic Radiology at the Li Ka Shing Faculty of Medicine, The University of Hong Kong. He is also the Deputy Director of the Tam Wing Fan Brain Imaging Research Laboratory at the Li Ka Shing Faculty of Medicine, The University of Hong Kong, and a junior fellow of the International Society for Magnetic Resonance in Medicine (ISMRM). Previously, he was a visiting assistant professor in the Department of Biomedical Engineering at City University of Hong Kong. He obtained his bachelor’s and master’s degrees from Xiamen University in 2014 and 2017, respectively, and his PhD degree from City University of Hong Kong in 2021. In 2022, he was elected as a Junior Fellow of the ISMRM, and received the Summa Cum Laude Merit Award and Magna Cum Laude Merit Award from ISMRM in 2021 and 2020, respectively. Additionally, he was awarded the Young Investigator Award from the OCSMRM in 2020 and the International CEST Conference in 2018. His current research focuses on magnetic resonance imaging (MRI), chemical exchange saturation transfer (CEST) MRI, artificial intelligence in medical imaging and neuroscience. He has published 40 papers in top international journals such as Science Advances, Nature Communications, Magnetic Resonance in Medicine, IEEE Journal of Biomedical and Health Informatics, and holds 7 authorized patents. He currently serves as an Associate Editor (Trainee) for the Journal of Magnetic Resonance Imaging and as a reviewer for journals such as Magnetic Resonance in Medicine, European Radiology, IEEE Transactions on Neural Networks and Learning Systems, and IEEE Transactions on Biomedical Engineering.

Dr Zhang is a research assistant professor in the Department of Rehabilitation Sciences at the Hong Kong Polytechnic University. She received a Bachelor of Engineering degree in Electronic Information Science and Technology from Zhengzhou University in 2012 ,and obtained her postgraduate qualifications in Master of Biomedical Engineering from Peking University in 2015 and a PhD in neuroscience from Hong Kong University in 2019. She underwent postdoctoral fellowship at the HKU Li Ka Shing Faculty of Medicine from 2019 to 2022.

Research by Dr Zhang focused on brain changes in different diseases or during the rehabilitation process using different MRI techniques. Her research includes evaluating the effects on the brain after intranasal insulin administration in Type-2 diabetic patients, small world networks and their relationship with hippocampal Glutamate concentration in healthy adults with the high-risk APOE4 gene, and brain changes in long COVID patients with olfactory dysfunction.

Dr Zhang currently intends to combine multi-modal MRI techniques, such as diffusion tensor imaging (DTI), functional MRI (fMRI) and Positron emission tomography (PET), with artificial intelligence and big data analysis, or other advanced algorithmic techniques to provide insights into the potentially accurate diagnosis and therapy development.